Caring for Asian patients from other cultures offers some unique challenges, whether these are recent immigrants to the U.S. or patients seen in overseas settings. Language is just the first obstacle and often professional interpreters are a necessity. Cultural expectations differ by country. High context Asian cultures can make it difficult to communicate even after language issues are resolved. Many illnesses present differently with physical complaints often masking mental health concerns. Familiarity with various Asian culture bound syndromes is essential.